On 2nd February 2023, Professor Huan Nguyen was invited to join a panel discussion at the Workshop “Engineering Digital Twins in Practice” hosted at Factory 2050 in AMRC Sheffield. The panel, chaired by Professor David Wagg (University of Sheffield), included other panelists John Patsavellas (Cranfield University), Jan Wolber (GE Healthcare), and Ali Nicholl (IOTICS). The benefits, challenges and specific use cases on Digital Twin technology were discussed and shared with 100+ in-person and online audiences. Prof. Nguyen presented some examples of the DT work at LDTRC for applications on smart factory and 6G mobile networks. The event also featured several other talks on DT and was ended with a tour of fantastic facilities at AMRC’s Factory 2050.